Bricef CF

Bricef-CF

Broad-spectrum antibiotic for bacterial infections

Bricef CF is a combination antibiotic containing cefoperazone and sulbactam, effective against a wide range of bacterial infections.

Overview

Bricef CF is a potent antibiotic combining cefoperazone, a third-generation cephalosporin, with sulbactam, a beta-lactamase inhibitor. This combination enhances its effectiveness against resistant bacteria by preventing bacterial cell wall synthesis and inhibiting beta-lactamase enzymes that degrade antibiotics. It is administered intravenously or intramuscularly for serious infections.

Manufactured under strict quality standards, Bricef CF is widely used in hospitals for its broad-spectrum activity and reliable efficacy. It is particularly effective for infections caused by gram-positive and gram-negative bacteria, including those resistant to other antibiotics.

Key Benefits:

  • Broad-spectrum coverage against resistant bacteria
  • Effective for severe infections in various body systems
  • Enhanced efficacy due to sulbactam’s beta-lactamase inhibition
  • Suitable for hospital-acquired infections
  • Clinically proven safety and effectiveness
Composition

Active Ingredients:

Ingredient Amount per Vial Function
Cefoperazone Sodium (eq. to Cefoperazone) 1000 mg Third-generation cephalosporin antibiotic that disrupts bacterial cell wall synthesis
Sulbactam Sodium (eq. to Sulbactam) 500 mg Beta-lactamase inhibitor that prevents antibiotic degradation

Free from gluten, lactose, and artificial preservatives. Consult a healthcare provider if allergic to cephalosporins or penicillins.

Indications

Recommended Uses:

Bricef CF is indicated for the treatment of infections caused by susceptible bacteria, including:

  • Respiratory tract infections (e.g., pneumonia)
  • Urinary tract infections
  • Skin and soft tissue infections
  • Intra-abdominal infections (e.g., peritonitis)
  • Septicemia
  • Bone and joint infections
  • Gynecological infections

Use only under medical supervision. Confirm bacterial susceptibility before treatment.

Dosage & Administration

Recommended Dosage:

Adults: 2-4 g/day (cefoperazone 1-2 g + sulbactam 0.5-1 g) in divided doses every 12 hours, adjusted based on infection severity.
Children: 40-80 mg/kg/day (cefoperazone) in 2-4 divided doses, as prescribed by a pediatrician.
Renal impairment: Dose adjustment required; consult a physician.

Administration:

  • Administer via intravenous infusion (over 15-30 minutes) or intramuscular injection
  • Reconstitute with sterile water or compatible diluent as per instructions
  • Follow aseptic techniques to prevent contamination

Do not exceed recommended doses. Monitor for superinfections during prolonged use.

Side Effects & Warnings

Common Side Effects:

  • Diarrhea or nausea
  • Injection site pain or irritation
  • Mild rash or itching

Serious Side Effects (Seek Medical Attention Immediately):

  • Severe allergic reactions (e.g., anaphylaxis, swelling)
  • Persistent diarrhea (sign of Clostridium difficile infection)
  • Liver dysfunction (yellowing of skin/eyes)
  • Blood disorders (e.g., low platelet count)

Contraindications:

Do NOT use Bricef CF if you:

  • Have a known allergy to cephalosporins, penicillins, or sulbactam
  • Have a history of severe hypersensitivity reactions
  • Are using certain medications without consulting a doctor
Storage Information

Storage Conditions:

  • Store below 25°C (77°F) in a dry place
  • Protect from light and moisture
  • Keep out of reach of children
  • Store in original vial until reconstitution

Shelf Life:

Bricef CF has a shelf life of 24 months from the date of manufacture when stored as recommended. Use reconstituted solution within 24 hours if stored at room temperature or 5 days if refrigerated.

Dispose of unused or expired medication through a pharmacy take-back program. Do not flush or discard in household trash.

Information provided is for educational purposes only. Always consult your healthcare provider before starting any medication. This product is available by prescription only in many countries. Follow your local regulations for proper acquisition and use of this medication.